Wolves 1 - 2 Manchester United
L
 23/05/2021 (Premier League)
Crewe Alexandra 1 - 0 Wolves
L
 17/07/2021 (Friendly)
Stoke City 1 - 1 Wolves
D
 31/07/2021 (Friendly)
Coventry City 1 - 2 Wolves
W
 01/08/2021 (Friendly)
Wolves 0 - 1 Celta Vigo
L
 07/08/2021 (Friendly)
Leicester City 1 - 0 Wolves
L
 14/08/2021 (Premier League)
Wolves 0 - 1 Tottenham Hotspur
L
 22/08/2021 (Premier League)
Nottingham Forest 0 - 4 Wolves
W
 24/08/2021 (LC)
Wolves 0 - 1 Manchester United
L
 29/08/2021 (Premier League)
Watford 0 - 2 Wolves
W
 11/09/2021 (Premier League)
Wolves 0 - 2 Brentford
L
 18/09/2021 (Premier League)
Wolves 2 - 2 Tottenham Hotspur
L
 22/09/2021 (LC)
Southampton 0 - 1 Wolves
W
 26/09/2021 (Premier League)
Wolves 2 - 1 Newcastle United
W
 02/10/2021 (Premier League)
Aston Villa vs Wolves 16/10/2021 (Premier League)
Leeds United vs Wolves 23/10/2021 (Premier League)
Wolves vs Everton 30/10/2021 (Premier League)
Crystal Palace vs Wolves 06/11/2021 (Premier League)